Each 15-minute podcast will provide an overview of the issue’s contents and relevant news in the field of basic/translational cardiovascular biology followed by...
This month on Episode 70 of Discover CircRes, host Cindy St. Hilaire highlights three articles featured in the February 28th issue of Circulation Research and the Compendium on Lifelong Care in Women: Applying a Sex- and Gender-Lens to Practice in the March 14th issue. This Episode also includes a discussion with Dr Matt Rossman and Sana Darvish from the University of Colorado, Boulder about their study, Preservation of Vascular Endothelial Function in Late Onset Postmenopausal Women. Article highlights: Huang, et al. Targeting CXCR3 in ICI-Mediated Myocarditis Ju, et al. RIC-Enhanced Efferocytosis on Stroke Recovery Halmos, et al. Cholesterol Efflux Pathways Control SMC Function Compendium on Lifelong Care in Women: Applying a Sex- and Gender-Lens to Practice
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33:56
Discover CircRes February 2025
This month on Episode 69 of Discover CircRes, host Cindy St. Hilaire highlights four articles featured in the January 31st and February 14th issues of Circulation Research. This Episode also includes a discussion with Dr Frank Conlon and graduate student Ike Emerson about their study, X Chromosome-Linked MicroRNAs Regulate Sex Differences in Cardiac Physiology. Article highlights: Huang, et al. Vps4a Safeguards Plasma Membrane Integrity Liu, et al. PPM1B Deubiquitination Promotes Arterial Stiffness Muralitharan, et al. GPR41/43 and Blood Pressure Park, et al. Ferroptosis and Its Consequences in Preeclampsia
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34:26
Discover CircRes January 2025
This month on Episode 68 of Discover CircRes, host Cindy St. Hilaire highlights four articles featured in the January 3rd and January 17th issues of Circulation Research. This Episode also includes a discussion with Drs Gianluigi Condorelli and Marinos Kallikourdis about their study Autoimmune-like Mechanism in Heart Failure Enables Preventative Vaccine Therapy. Article highlights: Yoshida, et al. FAP Vaccine Improves Cardiac Fibrosis Johansen, et al. TCF21 and Cardiac Fibrosis Pabon, et al. Endothelial METAP1 in Preeclampsia Mutchler, et al. ET-3/ETBR, Immune Cells, and Kidney Lymphatics
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34:19
Discover CircRes December 2024
This month on Episode 67 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the December 6th issues of Circulation Research. This Episode also includes a discussion with Drs Jesse Rowley and Shancy Jacob about their study, Mitofusin-2 Regulates Platelet Mitochondria and Function. Article highlights: Bardhan, et al. Sex Specific Roles of Microbiota in Hypertension Ma, et al. Kindlin-2 LLPS Controls Vascular Stability Wang, et al. CAR-Ms Alleviate Myocardial I/R Injury
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26:05
Discover CircRes November 2024
This month on Episode 66 of Discover CircRes, host Cindy St. Hilaire highlights articles featured in the October 25th and November 8th issues of Circulation Research. This Episode also includes a discussion with Dr Jil Tardiff and Dr Melissa Lynn about their study, Arg92Leu-cTnT Alters the cTnC-cTnI Interface Disrupting PKA-Mediated Relaxation. Article highlights: Lou, et al. Visualizing irAEs in Atherosclerosis Yoshii, et al. Defective Mitophagy Response in HFpEF Heart Zeller, et al. Shear Stress Dissociates C-Reactive Protein Chen, et al. EPHB4-RASA1 Regulation of Lymphatic Valvulogenesis
Each 15-minute podcast will provide an overview of the issue’s contents and relevant news in the field of basic/translational cardiovascular biology followed by an in-depth discussion of a featured article. This discussion will pull opinions from the podcast hosts, editorial team, research leaders and authors – both the corresponding authors as well as the trainee(s). We will provide lively discussions that give the listener a behind the scenes look at how science gets done and the implications of these fascinating discoveries.